ON HYPOPITUITARISM

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An Update on Subclinical Hypopituitarism

Subclinical deficiency of pituitary hormones represents an intermediate situation among normal pituitary secretion and overt hypopituitarism. Clinical hypopituitarism is associated with impaired morbidity and mortality, but there are not many studies on these topics in the subclinical setting. Moreover, clinical manifestations and diagnosis criteria are not well defined, so this entity is proba...

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Radiation-induced hypopituitarism.

The hypothalamic-pituitary unit is a particularly radiosensitive region in the central nervous system. As a consequence, hypopituitarism commonly develops after radiation treatments for sellar and parasellar neoplasms, extrasellar brain tumours, head and neck tumours, and following whole body irradiation for systemic malignancies. Increasing tumour-related survival rates provide an expanding po...

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ژورنال

عنوان ژورنال: BMJ

سال: 1936

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.3958.984